Parent page: Biogenic Amines Analysis

Biogenic Analysis

Histamine

Histamine in the presence of Putrescine and Cadaverine can cause scombroid poisoning (presence of “scombrotoxine” in tuna or mackerel). Clinical symptoms of Histamine poisoning can be:

CataneousGastroinestinalNeurologicalOther
RashNeaseaFacial, neckHyptension
UrticariaVomitingHeadacheBronchospasm
EdemaDiarrheaPalpitationsShock
FacialAbdominal crampsTingling, itching
NeckOral burning

Analysis of Biogenic amines is normally performed by using a dedicated amino acid analyser equipped with a special column and a special set of buffers. If applicable samples can also be tested according to an in-house developed HPLC-method for Tryptophan based Biogenic amines (e.g. tryptamine, 5-OH-tryptamine or serotonin).